Allergy Drugs and Their Side Effects
Types of Drugs | Generic or Chemical Names | Trade Names | Types of Allergy Treated | Most Common Side Effect |
Antihistamines | akylamine* (most commonly prescribed) | Actidil, Dimetane Extentabs, Polaramine, Polaramine Repetabs, Triten, Triten Tab-In | Hives (urticaria), contact dermatitis, eczema, hay fever (allergic rhinitis), | Drowsiness, nausea, abdominal discomfort, dry mouth |
athanolamine | Ambodryl, Benadryl, Clistin, Decapryn, Diafen, Dramamine, Hispril, SK-Diphenhydramine, Tavist | gastrointestinal allergy | ||
ethylenediamine* | Nivasal, PBZ, PBZ-SR | |||
phenothiazines | Phenergan, Tacaryl, Temaril | |||
piperazines | Bonine, Merezine | |||
miscellneous | Atarax, Optimime, Periactin, Vistaril | |||
Bischromones | cromolyn sodium | Intal, Lomudal | Asthma (allergic and exercise induced), gastrointestinal allergy | Throat irritation, hoarseness, coughing, wheezing. Safety during pregnancy not yet determined |
Bronchodilators | 1. Adrenergic agonists | Asthma, hives (occasionally) | Fear, anxiety, tenseness, restlessness, headache, weakness, dizziness, pallor, accentuated heartbeat, nausea, insomnia, tremor | |
albuterol | Proventil, Ventolin | |||
pehedrine | Ephedrine USP | |||
epinephrine | Adrenalin Chloride, Bronkaid Mist, Bronkophrine, Primatene M, Primatene Mist, Primatene P, Sus-Phrine | |||
isoetharine | Bronkometer, Bronkosol | |||
isoproterenol | Aerolone, Duo-Medihaler, Isuprel, Norisodrine | |||
metaproterenol | Aluprent, Metaprel | |||
protokylol | Ventaire | |||
terbutaline | Brethine Bricanyl | |||
2. Methylxanthines | Asthma | Irritation of stomach or intestines, nausea, abdominal cramps, heartburn, exacerbation of ulcers, temporary sleeplessness, nervousness | ||
aminophylline | Aminophyllin, Aminophylline, Phyllocontin | |||
oxtriphylline | Choledyl | |||
theophylline | Bronkodyl, Bronkodyl S-R | |||
Corticosteroids | 1. Aerosol | Hay fever, nasal polyps, asthma | Dry mouth, hoarseness, fungal infections of mouth and throat | |
beclomethasone dipropionate | Beclovent | Rinse mouth thoroughly with water after each use | ||
dexamethasone | Decadron Phospate Respihaler, Decadron Phospate, Turbinaire | |||
2. Systemic | All allergies, especially acute, chronic asthma; acute hives; drug reactions | Water retention, weight gain, susceptibility to bruising, stretch marks, more body hair, insomnia, uneasiness, leg cramps, "moon face." (most minor side effects likely more long term use at high doses). Suppression of adrenal hormones | ||
betamethasone | Celestone | |||
cortisone | Cortisone acetate | |||
dexamathesone | Decadron | |||
hydrocortisone | Many trade names | |||
methylprednisolone | Medrol, Methylprednisolone | |||
paramethasone | Haldrone | |||
triamcinolone | Aristocort | |||
3. Topical (creams, gels, ointments) | Variety of trade names | Rashes (especially eczema and contact dermatitis) | Burning sensations, irritation, itching, dryness, inflammation of hair follicles, acne, loss of pigmentation, thinning of skin, stretch marks, tendency of bruise easily, skin ulcers (Side effects depend on potency, concentration and duration of use) Contact dermatitis can result when cream, gel or ointment contains preservatives | |
betamethasone | ||||
desonide | ||||
desoximetasone | ||||
dexamathasone | ||||
flumethasone | ||||
fluocinolone acetonide | ||||
flurandrenolide | ||||
halcinonide | ||||
hydrocortisone | ||||
prednisolone | ||||
triamcinolone acetonide | ||||
Decongestants | naphazoline | Privine | Hay fever, gastrointestinal allergy | Nervousness, dizziness, nausea, rapid heartbeat Do not use nasal decongestants for more than 5 days. May prolong symptoms |
oxymetazoline | Afrin | |||
phenylephrine | Neo-Synephrine | |||
pseudoephredrine hydrochloride | Novafed, Sudafed | |||
tetrahydrozoline | Tyzine | |||
zymetazone | Otrivin | |||
Expectorants | iodides | Organidin, Potassium Iodide USP | Asthma | Nausea, abdominal cramps and diarrhea; unpleasant brassy taste and burning sensation in mouth and throat; sore teeth and gums; increased salivation |
quaifenesin | Glycotuss, Robitussin, 2/G | Asthma | none |
Source: Adapted from The Allergy Encyclopedia, by Craig T. Norbeck and Raymond G. Slavin (New York: New American Library, 1981). Physicians' Desk Reference (Oradell, N.J. Medical Economics Co. 1982).
* Found in many over the counter remedies for colds, hay fever and headaches.